Because the F16V2 (Blue or Red) is getting ALL its data from E1.31 input on CAT5, and E1.31 (or SACN) is the term for DMX over Ethernet, that means that DMX is the only thing that is available to go out those four RJ45 jacks. Yes, it can do Pixelnet, but Pixelnet is just DMX on pixel steroids. It cannot send true LOR protocol data
On the F16V2 Blue Boards, if you want to send DMX out to LOR controllers, it needs a crossover cable. Same with DMX out to Renard boards. But, if it is "standard" DMX, then a plain CAT5 patch cable works.
On the newer F16V2 Red Boards, the jumpers for LOR mean you don't need a crossover cable. It is still DMX but adjusted for LOR controllers. Renard still needs a crossover cable.
Of course, Dave Pitts is going to release new hardware for the F16V2 Red (only) that will allow the board to run FSEQ files from a uSD card and even be synchronized like an FPP Remote if desired. But, the serial ports will still only put out DMX or Pixelnet as described above.